Description:

Briganix 90mg (Brigatinib) ‘s brand name is ALUNBRIG® by Takeda Pharmaceutical. Briganix 90mg is a generic ALK positive metastatic NSCLC medicine from Beacon, which is a listed and the largest generic pharmaceutical manufacturer in Bangladesh.

Briganix 30 Tablets

Brigatinib(Briganix) 90 mg
Price

$425

Briganix 90mg (Brigatinib) ‘s brand name is ALUNBRIG® by Takeda Pharmaceutical. Briganix 90mg is a generic ALK positive metastatic NSCLC medicine from Beacon, which is a listed and the largest generic pharmaceutical manufacturer in Bangladesh.

Brigatinib (Brigatinib, also translated as: guitar guitar or bogtinib, developed code: AP26113) is a potent inhibitor of tyrosine kinase. On April 28, 2017, Buginib was approved by the US FDA to be marketed for the treatment of ALK-positive patients with locally advanced or static non-small cell lung cancer who developed progression or intolerance after crizotinib treatment. Bugatinib inhibits ALK and ALK fusion proteins, thereby inhibiting tumor growth. In vitro and in vivo tests, Buginib showed a good inhibitory effect. Therefore, it has also obtained the FDA-approved breakthrough therapy certification and orphan drug qualification.  

Recommended Dose:
90 mg orally once daily for the first 7 days; if tolerated, increase to 180 mg orally once daily. May be taken with or without food.

Lung problems. ALUNBRIG may cause severe or life-threatening swelling (inflammation) of the lungs any time during treatment, and can lead to death. These lung problems happen especially within the first week of treatment with ALUNBRIG. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

o cough with or without mucus o chest pain o fever

  High blood pressure (hypertension). ALUNBRIG may cause high blood pressure. Your healthcare provider will check your blood pressure before starting and during treatment with ALUNBRIG. Tell your healthcare provider right away if you get headaches, dizziness, blurred vision, chest pain or shortness of breath.

  Slow heart rate (bradycardia). ALUNBRIG may cause very slow heartbeats that can be severe. Your healthcare provider will check your heart rate during treatment with ALUNBRIG. Tell your healthcare provider right away if you feel dizzy, lightheaded, or faint during treatment with ALUNBRIG. Tell your healthcare provider if you start to take or have any changes in heart or blood pressure medicines.

  Vision problems. ALUNBRIG may cause vision problems. Your healthcare provider may stop ALUNBRIG and refer you to an eye specialist if you develop severe vision problems during treatment with ALUNBRIG. Tell your healthcare provider right away if you have any loss of vision or any change in vision, including: o double vision o light hurting your eyeso seeing flashes of light o new or increased floaters o blurry vision

   Muscle pain, tenderness, and weakness (myalgia). ALUNBRIG may increase the level of an enzyme in your blood called creatine phosphokinase (CPK), which may be a sign of muscle damage. Your healthcare provider will do blood tests to check your blood levels of CPK during treatment with ALUNBRIG. Tell your healthcare provider right away if you get new or worsening signs and symptoms of muscle problems, including unexplained muscle pain or muscle pain that does not go away, tenderness, or weakness.

   Inflammation of the pancreas (pancreatitis). ALUNBRIG may increase enzymes in your blood called amylase and lipase, which may be a sign of pancreatitis. Your healthcare provider will do blood tests to check your pancreatic enzyme blood levels during treatment with ALUNBRIG. Tell your healthcare provider right away if you get new or worsening signs and symptoms of pancreatitis, including upper abdominal pain that may spread to the back and get worse with eating, weight loss, or nausea.

  High blood sugar (hyperglycemia). ALUNBRIG may increase your blood sugar levels. Your healthcare provider will do blood tests to check your blood sugar levels before starting and during treatment with ALUNBRIG. Your healthcare provider may need to start or change your blood sugar medicine to control your blood sugar levels. Tell your healthcare provider right away if you get new or worsening signs and symptoms of hyperglycemia, including:

o trouble breathing or shortness of breath

o feeling very thirsty o feeling sick to your stomach

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