Elopag (Eltrombopag) 50 MG – 28 Tablets

Description

Elopag 50 mg (Eltrombopag ) is an orally bioavailable, small-molecule TPO-receptor agonist that reaction with the transmembrane domain of the human TPO-receptor and initiates signaling cascades that induce proliferation and differentiation from bone marrow progenitor cells. Elopag is available in tablet form for oral administration.

• Improves chronic ITP & SAA effectively.
• Effective in chronic hepatitis C related thrombocytopenia.
• Increases & maintains platelet counts.

Elopag (Eltrombopag) 50 mg using to treatment of low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when various other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. Eltrombopag newly approve (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.

Uses Elopag

Side Effects 

Thrombocytopenia

A condition in which there is a lower-than-normal number of platelets in the blood. It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues.

Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries.

A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000 per microliter.

Signs and Symptoms

Thrombocytopenia signs and symptoms may include:

•  Easy or excessive bruising (purpura).
•  Superficial bleeding into the skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on the lower legs.
•  Prolonged bleeding from cuts.
•  Bleeding from your gums or nose.
•  Blood in urine or stools.
•  Unusually heavy menstrual flows.
•  Fatigue.
•  Enlarged spleen.
•  Jaundice.

Causes 

Thrombocytopenia caused due to:

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