Description
Introduction of Xeljanz
Xeljanz generic name is tofacitinib, is an oral medication used to treat various inflammatory conditions. It belongs to a class of drugs called Janus kinase (JAK) inhibitors, which play a crucial role in managing autoimmune diseases by modulating the immune system’s activity.
At A Glance of Xeljanz Medicine:
| Xeljanz Generic Name | : Tofacitinib |
| Manufacturer | : Pfizer Inc |
| Formulation | : Tablet |
| Strength | : 5 mg |
| Quantity | : 60 Tablets |
| Storage | : Below 30°C |
| Registrations | : Export Only |
| Price | : $4500.00 |
Mechanism of Action
It functions by inhibiting Janus kinases, enzymes that play a crucial role in the signaling pathways of numerous cytokines and growth factors essential for blood cell formation and immune function. By blocking these pathways, it reduces the inflammatory response, thereby alleviating symptoms associated with autoimmune conditions.
Why Xeljanz Used For?
It is approved for treating several conditions:
- Rheumatoid Arthritis (RA):
It is indicated for adults with moderate to severe active rheumatoid arthritis (RA) who have not responded adequately to or cannot tolerate methotrexate. Patients can use it alone or in combination with methotrexate or other non-biologic disease-modifying antirheumatic drugs (DMARDs).
- Psoriatic Arthritis (PsA):
Approved for adults with active psoriatic arthritis (PsA) who have not responded adequately to or cannot tolerate methotrexate or other DMARDs.
- Ulcerative Colitis (UC):
Used to treat adults with moderate to severe active ulcerative colitis (UC) who have not responded adequately to or cannot tolerate TNF blockers.
- Ankylosing Spondylitis (AS):
Recommended for adults with active ankylosing spondylitis (AS) who haven’t had good results from standard treatments.
- Polyarticular Course Juvenile Idiopathic Arthritis (pcJIA):
Approved for children 2 years and older with active polyarticular juvenile idiopathic arthritis (pcJIA).
Administration and Dosage
Xeljanz is available in two formulations:
- Immediate-release tablets: Typically taken twice daily.
- Extended-release tablets: Taken once daily.
Doctors determine the specific dosage and regimen based on the condition being treated. They also take into account how severe the disease is, as well as the patient’s overall health and how they respond to the treatment.
Xeljanz Price
Xeljanz cost per month starts from $30 to $4500.
Side Effects
Common side effects of Xeljanz include:
- Upper respiratory tract infections
- Headache
- Diarrhea
- Nasopharyngitis
- Increased cholesterol levels
Contraindications and Precautions
Patients who are allergic to it should not take it. Doctors should be careful with patients who have a history of long-lasting or repeated infections, serious liver issues, or blood clots. They also recommend checking blood counts, liver enzymes, and cholesterol levels regularly during treatment.
Navigating Patient Assistance
Getting a Xeljanz prescription filled can be a financial burden without the right support. Thankfully, patient assistance programs like the Pfizer Patient Assistance Program can help eligible individuals access this medicine at a reduced or even zero cost. These programs often support patients with limited or no insurance by covering a portion of the medication expense. Additionally, navigating the prior authorization process with your healthcare provider can help ensure that your insurer approves it as a medically necessary prescription drug, ultimately saving time and money. Always ask your doctor or pharmacist about cost-saving opportunities and support programs available for Xeljanz or Xeljanz XR.
Prescription, Cost, and Insurance Coverage
It’s also known by its generic name tofacitinib, is a prescription drug primarily used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Available as Xeljanz or Xeljanz XR, it may come in both tablet and oral solution forms, offering flexible dosing options for different patient needs. Since Xeljanz 5 mg is a specialty medication, the cost can vary significantly based on your insurance plan, pharmacy, and dosage. Some patients face high Xeljanz price quotes without proper coverage, which is why understanding insurance coverage and prior authorization is crucial before starting treatment.
Conclusion
Xeljanz is a big improvement in treating different autoimmune diseases, providing a pill option instead of injectable biologics. It effectively helps reduce inflammation and improves the quality of life for patients with long-term inflammatory conditions, making it a valuable treatment choice. However, because it can cause serious side effects, healthcare professionals need to carefully choose the right patients and keep a close eye on them during treatment.
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