Sofosbuvir-Velpatasvir
Sofosbuvir-Velpatasvir
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Sofosbuvir Velpatasvir Price
Sofosbuvir Velpatasvir is a potent antiviral drug used to treat chronic hepatitis C virus (HCV) infection. This combination therapy combines two active ingredients: sofosbuvir, a nucleotide analog polymerase inhibitor that blocks replication of viral RNA, and velpatasvir, an NS5A inhibitor that disrupts viral assembly and replication. Effective across all six major HCV genotypes, Sofosbuvir/Velpatasvir serves as a versatile and pan-genotypic treatment option. Sofosbuvir-Velpatasvir offers a convenient once-daily oral therapy that has revolutionized the treatment landscape, leading to high rates of sustained virologic response (SVR), which is considered a definitive cure for hepatitis C in the majority of patients.
Sofosbuvir 400 mg
- Chronic HCV Infection: Effective against all major HCV genotypes (1-6) when used in combination with other antiviral agents.
- HCV with Cirrhosis: Suitable for both compensated and decompensated cirrhosis.
- HCV/HIV-1 Co-infection: Used in patients co-infected with HCV and HIV-1.
> Sofosbuvir is not used alone, it is always combined with Velpatasvir.
Velpatasvir 100 mg
- Chronic HCV Infection: Effective across all genotypes.
- HCV with Cirrhosis: Used in patients with compensated or decompensated cirrhosis.
- HCV/HIV-1 Co-infection: Treats patients co-infected with HCV and HIV-1.
> Velpatasvir is not used alone; it is always combined with Sofosbuvir.
Side Effects of Sofosbuvir and Velpatasvir
- Headache
- Fatigue
- Nausea
- Diarrhea
- Insomnia
- Anemia (low red blood cell count)
- Elevated Liver Enzymes
- Dizziness
- Weakness
- Rash
- Muscle pain
- Low blood pressure
- Liver problems
- Shortness of breath
- Bradycardia (slow heart rate)
Warnings of Sofosbuvir Velpatasvir
1. Risk of Hepatitis B Reactivation: Patients with a history of hepatitis B virus (HBV) infection should be monitored for HBV reactivation.
2. Liver Function Monitoring: Regular monitoring of liver function is recommended, especially in patients with cirrhosis or liver impairment.
3. Drug Interactions: Potential interactions with other medications, including antiretrovirals and certain anticonvulsants, may affect efficacy or increase side effects.
4. Pregnancy Category: Use with caution during pregnancy, and effective contraception is advised as safety during pregnancy has not been established.
Available Brands and Pricing List:
Brand Name |
Manufacture |
Quantity |
Cost in USD |
| Panovir |
Incepta Pharma |
28 Tablets |
$85 |
| Sofosvel |
Beacon Pharma |
28 Tablets |
$120 |
| Velpanex |
Everest Pharma |
28 Tablets |
$85 |
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