Sunitinib is a targeted therapy used to treat a variety of cancers, including advanced or metastatic renal cell carcinoma (RCC), unresectable or imatinib-resistant gastrointestinal stromal tumors (GISTs), and unresectable, locally advanced or metastatic pancreatic neuroendocrine tumors. It inhibits multiple receptor tyrosine kinases important in tumor growth and angiogenesis. By targeting these pathways, sunitinib helps slow or stop cancer progression. Additionally, it may be used off-label for other cancers based on clinical needs and patient-specific factors.

 

Sunitinib 50 mg

Doctors commonly use Sunitinib 50 mg, a targeted cancer therapy drug, to inhibit multiple receptor tyrosine kinases involved in the growth and spread of cancer cells. They specifically prescribe this dose for the treatment of advanced or metastatic renal cell carcinoma (RCC), unresectable or imatinib-resistant gastrointestinal stromal tumors (GISTs), and metastatic pancreatic neuroendocrine tumors (PNETs).

 

Sunitinib 25 mg

Doctors use Sunitinib 25 mg as a targeted therapy to treat certain types of cancer, including advanced or metastatic renal cell carcinoma (RCC), gastrointestinal stromal tumors (GISTs), and metastatic pancreatic neuroendocrine tumors (NET). They often choose the 25 mg strength for patients who require a lower dose due to side effects or other medical considerations, or as part of a dose adjustment during treatment.

 

Sunitinib 12.5 mg

The lowest available strength of sunitinib is 12.5 mg. Doctors often prescribe this lower dose for patients who need it because of side effects or certain health conditions. They are primarily used to treat advanced or metastatic renal cell carcinoma (RCC), unresectable or imatinib-resistant gastrointestinal stromal tumors (GISTs), and metastatic pancreatic neuroendocrine tumors (PNETs).

 

Sunitinib side effects

• Fatigue
• Nausea and vomiting
• Diarrhea
• Skin rash and hand-foot syndrome
• High blood pressure (hypertension)
• Mouth sores
• Bleeding
• Thyroid dysfunction (hypothyroidism/hyperthyroidism)
• Heart problems (heart failure, heart attack)
• Liver toxicity
• Low blood cell counts (anemia, neutropenia, thrombocytopenia)
• Swelling (edema)

 

Warnings of Sunitinib:

1. Cardiovascular risk: Possibility of heart failure, heart attack, and high blood pressure.

2. Liver toxicity: risk of liver damage; Regular monitoring of liver function is required.

3. Risk of bleeding: Gastrointestinal bleeding increases the risk of serious bleeding.

4. Thyroid dysfunction: This may cause hypothyroidism or hyperthyroidism; Thyroid function should be monitored.

5. Hematologic Toxicity: Low blood cell count, increased risk of infection, anemia, and bleeding.

 

Available Brands and Pricing List:

Brand Name	Manufacture	Quantity	Sunitinib price in USD
Sunitix 50 mg	Beacon Pharma	28 Capsules	$215.00
Sunitix 25 mg	Beacon Pharma	28 Capsules	$165.00
Sunitix 12.5 mg	Beacon Pharma	28 Capsules	$110.00

 

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