Description

Anib 40 mg Tablet: Uses, Dosage, Side Effects, and Price

 

Summary: 

Anib 40 mg contains the active ingredient Afatinib tablet manufactured by Drug International Ltd. It is used for specific types of EGFR mutation-positive non-small cell lung cancer (NSCLC). Doctors prescribe it when a patient needs a targeted therapy that works directly on cancer cell growth signals.

 

What is Anib 40 mg?

Anib 40 mg is a targeted cancer treatment. It belongs to a group called tyrosine kinase inhibitors (TKIs). Doctors prescribe it for patients who have EGFR mutation-positive metastatic NSCLC. These mutations are found through an approved diagnostic test.

Anib blocks abnormal signals that help cancer cells grow. When the drug stops those signals, cancer cells lose their ability to multiply.

In other words, lung cancer diagnosis changes everything. You need a treatment that targets the problem directly. Anib 40 mg represents a significant step forward in targeted cancer therapy. It is not just another pill; it is a precise tool designed to block the signals that allow cancer cells to grow.

It is specifically designed for Non-Small Cell Lung Cancer (NSCLC). It works best for patients whose cancer has specific genetic mutations.

 

 Product  Features Highlights:

Feature	Details
Brand Name	Anib
Generic Name	Afatinib
Strength	40 mg (Also available in other strengths)
Indication	Non-small cell lung cancer
Drug Class	Irreversible ErbB Family Blocker / TKI
Therapeutic Class	Tyrosine Kinase Inhibitor (Antineoplastic)
Form	Oral Tablet
Manufacturer	Drug International Ltd.
Primary Use	EGFR-mutation positive NSCLC
Administration	Oral Tablet (Once Daily)
Storage	Below 30°C, away from light.
Prescription Status	Prescription Required (Rx Only)
Price	$90.00
Registrations	Export Only
Exported By	EmergencyDrug (Online Pharmacy | Worldwide Shipping)

 

Anib 40 mg price in USA/ Canada/ UK/ Austrlia/ New Zealand/ Saudi Arabia/ UAE/ Qatar/ Yemen/ Bahrain/ Jordan/ Kuwait/South Africa/ Europe: $90.00 (per pack)

Disclaimer: Anib is a prescription-only medicine. You must consult a registered physician before starting this treatment.

Indications of Anib

Anib 40 mg is used to treat people with advanced NSCLC who have certain changes in the EGFR gene, which can be found by an FDA-approved test. It works especially well when other methods haven’t worked or aren’t right for the person.

 

Composition: Each Anib pill has 40 mg of Afatinib, which was carefully chosen to be absorbed and work well. Most of the time, the pills are oval and covered to make them easier to take.

Anib 40 mg offers a powerful option for fighting EGFR-mutated Non-Small Cell Lung Cancer. By irreversibly binding to cancer receptors, it stops tumor growth in its tracks.

Success with this medication relies on strict adherence: take it on an empty stomach, manage side effects proactively, and communicate openly with your doctor.

 

When Doctors Use Anib 40 mg?

1. EGFR Mutation-Positive Metastatic NSCLC

Doctors use Anib 40 mg as a first-line therapy when the tumor has non-resistant EGFR mutations, such as:

• Exon 19 deletion
• Exon 21 L858R substitution

These mutations activate cancer growth pathways. Anib helps slow that process down.

Limitation

• It does not work well for tumors with resistant EGFR mutations.

2. Previously Treated, Metastatic Squamous NSCLC

Anib is also used after patients have already received platinum-based chemotherapy but still show disease progression.

 

The Mechanism of Action: How It Works?

To understand how Anib works, imagine a switch.

Cancer cells often have “switches” on their surface called receptors. When these switches are flipped on, they tell the cell to divide and grow uncontrollably. In many lung cancers, a protein called EGFR (Epidermal Growth Factor Receptor) acts as this stuck switch.

Anib 40 mg (Afatinib) binds permanently (covalently) to these kinase domains (EGFR, HER2, and HER4).

• It attaches to the receptor.
• It blocks the signal that triggers cell growth.
• It creates “downregulation,” essentially shutting down the cancer cell’s ability to multiply.

This action causes tumor shrinkage and delays the progression of the disease.

 

Who Should Take Anib 40 mg?

Doctors prescribe Anib 40 mg for specific types of lung cancer. It is not for everyone. Your oncologist will likely perform a genetic test on your tumor before prescribing it.

1. First-Line Treatment for Metastatic NSCLC

It is used for patients with metastatic Non-Small Cell Lung Cancer (NSCLC) who have non-resistant EGFR mutations.

• Common mutations: Exon 19 deletions or Exon 21 (L858R) substitution.
• Limitation: It is not proven effective for “resistant” mutations.

2. Squamous NSCLC

It is also indicated for patients with metastatic squamous NSCLC if the cancer has progressed after receiving platinum-based chemotherapy.

Dosage and Administration Guide

Taking Anib 40 mg correctly is vital for its success. The medicine needs specific conditions to be absorbed properly by your body.

Recommended Dosage

Standard Dose: One 40 mg tablet orally, once daily.

Duration: Continue treatment until disease progression or as long as your body tolerates the drug.

The “Empty Stomach” Rule

You must strictly follow this rule for the drug to work:

• Take Anib at least 1 hour before a meal.
• OR take it at least 2 hours after a meal.
• Do not take it with food. Food can block the medicine from entering your bloodstream.

 

Dosing for Special Conditions

Severe Renal Impairment: If your kidneys are not functioning well (GFR 15-29 mL/min), the doctor may lower the dose to 30 mg once daily.

Missed Dose: If you forget a pill, check the time. Is your next dose more than 12 hours away? If yes, take it. If your next dose is within 12 hours, skip the missed dose. Never double up.

Pediatric Use: Not recommended. Safety is not established.

 

Side Effects and Management

Anib 40 mg is potent. While it attacks cancer, it can cause side effects. Most are manageable if you catch them early.

Common Side Effects

• Diarrhea: This is the most common issue. It can lead to dehydration.
• Skin Reactions: Acne-like rash, dry skin, or inflammation around fingernails (paronychia).
• Stomatitis: Sores inside the mouth.

Serious Side Effects

• Interstitial Lung Disease (ILD): Rare but serious lung inflammation.
• Hepatic Toxicity: Liver damage.
• Keratitis: Eye inflammation causing blurred vision or sensitivity to light.

Drug Interactions

Some medicines change how Anib 40 mg works. They can either make it toxic or stop it from working.

Drugs that INCREASE Anib levels (P-gp Inhibitors): 

• Ritonavir
• Cyclosporine A
• Ketoconazole / Itraconazole
• Erythromycin
• Verapamil / Amiodarone

Drugs that DECREASE Anib levels (P-gp Inducers): 

• Rifampicin
• Carbamazepine
• Phenytoin
• St. John’s Wort

Action Plan: Show your doctor your full list of medications, including herbal supplements, before starting treatment.

 

Who Should Avoid Anib 40 mg?

Do not take Anib if you:

• Have a known allergy to Afatinib
• Are hypersensitive to any ingredients

 

Use During Pregnancy and Breastfeeding

Pregnancy

Afatinib can harm the fetus.

Doctors avoid prescribing Anib during pregnancy.

Breastfeeding

Not recommended during treatment and for

2 weeks after the last dose.

 

Overdose Information

High doses may cause:

• Nausea
• Vomiting
• Abdominal pain
• Headache
• Dizziness

Seek immediate medical help if overdose is suspected.

 

Therapeutic Class

• Tyrosine Kinase Inhibitor (TKI)

 

Storage Instructions

• Keep under 30°C
• Store in a cool, dry place
• Protect from sunlight
• Keep out of children’s reach

 

Why Buy from Us :

• 100% genuine products
• Licensed exporter
• Discreet packaging
• Customer support 

 

Pricing and Prescription Pathway

In the pharmaceutical market, targeted therapies like Afatinib are high-value medications.

Prescription: A valid prescription from a registered oncologist is mandatory.

Insurance: Many insurance plans cover oral chemotherapy drugs. Check with your provider regarding “Specialty Pharmacy” benefits.

Financial Assistance: Manufacturers often have patient assistance programs. Ask your pharmacy if you qualify for support. 

Online Pharmacy That Exports Generic Medicines: Alternatively, you can purchase Anib 40 mg (Afatinib) at a lower costs than the brand ones from EmergencyDrugDotCom.

 

Final Word

Anib 40 mg plays a strong role in treating EGFR mutation-positive NSCLC, especially when fast and targeted cancer control is needed. Its action is powerful, so monitoring side effects is important. Always follow your oncologist’s instructions, keep up with medical tests, and don’t ignore early symptoms of adverse reactions.

 

Frequently Asked Questions

Here are answers to the most common questions about Anib 40 mg.

1. How quickly does Anib 40 mg start working?

Ans: Response varies by patient. However, clinical trials often show tumor shrinkage within the first few months of treatment. Your doctor will use CT scans to monitor progress.

2. Is Anib 40 mg considered chemotherapy?

Ans: No. It is a “Targeted Therapy” (Tyrosine Kinase Inhibitor). Traditional chemo kills all fast-growing cells. Anib specifically targets the EGFR protein on cancer cells, often resulting in fewer systemic side effects than chemo.

3. Can I cut or crush the tablet if I can’t swallow it?

Ans: Generally, you should swallow the tablet whole with water. However, if you have trouble swallowing, the label for Afatinib allows dispersing the tablet in plain water (no other liquids). Drink the dispersion immediately. Consult your pharmacist for the exact method.

4. What should I eat while taking Anib?

Ans: There is no specific diet, but you must avoid grapefruit and grapefruit juice, as they can interact with the drug. Also, avoiding spicy or greasy foods can help manage diarrhea, a common side effect.

5. Does Anib cause hair loss?

Ans: Hair changes can occur, but total hair loss (alopecia) is less common with Anib than with traditional chemotherapy. You might experience changes in hair texture or thinning.

[Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult with a registered healthcare professional for diagnosis and treatment.]