Elbonix 25 MG (Eltrombopag) – 28 Tablets

Description

Elbonix 25 mg tablet is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. Platelets help to reduce or prevent bleeding.

Product Features:

Introduction

Elbonix 25 oral tablet is available as a brand-name drug. It’s not available as a generic drug. It comes in two forms: oral tablet and oral suspension. Eltrombopag is an orally bioavailable, small-molecule TPO-receptor agonist that interacts with the transmembrane domain of the human TPO-receptor. The medicine is a stimulator of STAT and JAK phosphorylation. Unlike recombinant TPO or romiplostim, Eltrombopag does not activate the AKT pathway in any way. It should be noted that when given to patients with aplastic anemia, other lineages besides platelet count were increased, suggesting that either eltrombopag enhanced the effect of TPO in vivo; or there is a yet uncovered mechanism of action at work.

Uses

Elbonix 25 is used for low platelet count due to ITP or HCV infection. That treat low platelet count due to chronic immune (idiopathic), thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infection. Eltrombopag is also use to treat severe aplastic anemia.

1. Chronic Immune Thrombocytopenia (ITP)

• ITP is a condition where your immune system mistakenly attacks and destroys your platelets.
• It helps your body make more platelets, reducing the risk of bleeding. It’s usually given to people who have tried other treatments, like steroids or immune globulin, but didn’t get better.

2. Thrombocytopenia in People with Hepatitis C

• Hepatitis C is a liver disease caused by the hepatitis C virus. Sometimes, the treatment for this disease can lower platelet counts.
• It is given to help raise platelet levels so that people can continue their hepatitis C treatment without interruptions.

3. Severe Aplastic Anemia

• Aplastic anemia is a condition where your bone marrow doesn’t make enough new blood cells, including platelets.
• It can be used when other treatments haven’t worked, to help increase platelet production and improve blood counts.

How to Take

• Dosage: Always follow your doctor’s instructions on how to take Elbonix. Usually, it’s taken once a day.
• With or Without Food: It’s important to take Elbonix either one hour before or two hours after eating, especially foods high in calcium, like dairy products, because calcium can affect how the medicine works.
• Regular Check-ups: Your doctor will do regular blood tests to check your platelet levels and see how well the medicine is working.

Side effects

Eltrombopag can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking eltrombopag. This list does not include all possible side effects.

More common side effects

The more common side effects of eltrombopag can include:

• Anemia
• Nausea
• Fever
• Tiredness
• Cough
• Headache
• Diarrhea
• Flu
• Loss of appetite

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Interactions that increase your risk of side effects

Increased side effects from other drugs: Taking eltrombopag with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:

• Bosentan, ezetimibe, glyburide, olmesartan, repaglinide, rifampin, valsartan, imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, sulfasalazine, and topotecan. Your doctor may lower your dosage of these drugs if needed.
• Cholesterol-lowering drugs such as rosuvastatin, atorvastatin, fluvastatin, pitavastatin, pravastatin, and simvastatin. Increased side effects can include muscle pain. Your doctor may lower the dosage of your cholesterol drugs.

Interactions of medicine effective

When use with eltrombopag, these drugs can make eltrombopag less effective. This means it won’t work as well to treat your condition. This is because the amount of eltrombopag in your body may be decreased. Examples of these drugs include:

• Antacids, vitamins, or supplements that contain calcium, aluminum, iron, selenium, zinc, or magnesium. To avoid interactions, you should take eltrombopag two hours before or four hours after taking any of these products.

Warnings for other groups

Pregnant women

• There haven’t enough studies done in humans to be certain how this drug might affect a pregnancy. Research in animals has shown negative effects to the pregnancy when the mother takes the drug. However, animal studies don’t always predict the way humans would respond.
• Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only use if the potential benefit justifies the potential risk.
• If you become pregnant while taking this drug, call your doctor right away.

Breastfeeding women

• This medication is not recommended for use while breastfeeding. This drug may pass into breast milk and cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

Children

• This drug has not studied in children younger than 1 year with chronic immune thrombocytopenia. It should not use in children younger than 1 year for this condition.
• This drug has not studied in children younger than 2 years with definitive immunosuppressive therapy-naïve severe aplastic anemia (in combination with other medications). It should not use in children younger than 2 years for this condition. (Therapy naïve means the condition has not treated before.)
• This drug has not established as safe or effective for use in children with thrombocytopenia associated with chronic hepatitis C virus infection and refractory severe aplastic anemia. It should not use in people younger than 18 years with these conditions.

If you miss a dose

If you miss a dose, wait and take your next scheduled dose. Do not take more than one dose of this drug in one day.

Visit our hepatitis C related other product here.