Palboxen (Palbociclib) 125Mg – 21 Capsules

Description

Palboxen (Palbociclib) 125mg is the generic name for the trade name drug Ibrance. In some cases, health care professionals may use the trade name Ibrance when referring to the generic drug name Palbociclib. Palbociclib use in combination with letrozole (an aromatase inhibitor) to treat postmenopausal women with estrogen receptor (ER) positive, HER2 negative advanced breast cancer.

Product Features:

Palboxen (Palbociclib) is the generic name for the trade name drug Ibrance. Health care professionals may use the trade name Ibrance when referring to the generic drug name Palbociclib.

Usage and dosage

The recommended starting dose is 125 mg once a day, combined with Letrazao, with meals, for a total of 21 days, and then stop taking the drug for 7 days.

How to use Palboxen 125

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Palboxen 125 is to be taken with food.

Common side effects

• Fatigue
• Fever
• Hair loss
• Rash
• Vomiting
• Diarrhea
• Nausea
• Decreased blood cells (red cells, white cells, and platelets)
• Infection
• Decreased appetite

How Palboxen Works

Targeted therapy is the result of about 100 years of research dedicated to understanding the differences between cancer cells and normal cells. To date, cancer treatment has focused primarily on killing rapidly dividing cells because one feature of cancer cells is that they divide rapidly. Unfortunately, some of our normal cells divide rapidly too, causing multiple side effects.

Targeted therapy is about identifying other features of cancer cells. Scientists look for specific differences in the cancer cells and the normal cells. This information use to create a targeted therapy to attack the cancer cells without damaging the normal cells, thus leading to fewer side effects. Each type of targeted therapy works a little bit differently but all interfere with the ability of the cancer cell to grow, divide, repair and/or communicate with other cells.

Researchers agree that targeted therapies are not a replacement for traditional therapies. They may best use in combination with traditional therapies. More research need to identify which cancers best treat with targeted therapies and to identify additional targets for more types of cancer.

Mechanism of Action

Palboxen (Ibrance®) is a drug that can use along with an aromatase inhibitor to treat women with advanced hormone receptor-positive breast cancer. Palboxen is a reversible small molecule cyclin-dependent kinase (CDK) inhibitor. The drug blocks proteins in the cell called cyclin-dependent kinase (CDK) 4 and CDK 6. In hormone positive breast cancer cells, blocking these proteins helps stop the cells from dividing to make new cells. It helps prevent the cells from moving from G1 to S cell cycle phase in the division process. This slows cancer growth. The combination of Palboxen and aromatase inhibitor (e.g. letrozole) is more effective compare with each agent alone.

Quick Tips

• Take it with food, preferably at the same time every day.
• If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose.
• Use effective contraception method to prevent pregnancy while taking this medicine.
• It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
• You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
• Do not stop taking the medication without talking to your doctor first.

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