Description
Summary
Telabee 25 mg tablet (Tenofovir Alafenamide) is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Manufactured by Jenphar Bangladesh Limited, an affiliate of Radiant Pharmaceuticals Limited, this medication offers a safer kidney and bone profile compared to older tenofovir formulations.
Introduction
Living with chronic hepatitis B (HBV) can be challenging, but modern medicine offers effective treatments like Telabee 25 mg (Tenofovir Alafenamide) tablet.
This medication helps suppress the virus, reducing liver damage and improving quality of life.
What is Telabee 25 mg Tenofovir Alafenamide?
Telabee is a tablet formulation containing Tenofovir Alafenamide (TAF) 25 mg. It is a prodrug of Tenofovir, a nucleotide reverse transcriptase inhibitor (NRTI), designed for improved kidney and bone safety compared to its predecessor, Tenofovir Disoproxil Fumarate (TDF).
Key Benefits:
✔ Lower kidney toxicity compared to Tenofovir Disoproxil Fumarate (TDF)
✔ Better bone safety—reduced risk of bone density loss
✔ Highly effective in suppressing HBV viral load
✔ Once-daily dosing for convenience
Key Features of Telabee 25 mg Tablet
| Feature | Details |
| Active Ingredient | Tenofovir Alafenamide 25 mg |
| Manufacturer | Jenphar Bangladesh Ltd. |
| Therapeutic Class | Antiviral / NRTI |
| Used For | Chronic Hepatitis B (HBV); HIV/ AIDS (With Combination of other medicines) |
| Dosage Form | Film-coated tablet |
| Recommended Dose | 25 mg once daily with food |
| Pack Size | 10 Tablets per pack |
| Telabee 25 mg Price | $40.00 |
How Does Telabee 25 mg Work? (Mechanism of Action)
Tenofovir Alafenamide is a prodrug that gets converted into tenofovir inside liver cells. It then blocks the HBV reverse transcriptase enzyme, preventing the virus from multiplying.
Why Choose TAF Over TDF (Tenofovir disoproxil)?
| Parameter | Telabee (TAF 25 mg) | Tenofovir DF (TDF) |
| Kidney Safety | ✅ Lower risk of kidney damage | ❌ Higher risk |
| Bone Safety | ✅ Less bone density loss | ❌ More bone issues |
| Dosage | 25 mg daily | 300 mg daily |
| Efficacy | Similar viral suppression | Similar viral suppression |
Indications of Telabee 25 mg
✔ Chronic Hepatitis B (HBV) in adults with compensated liver disease
✔ Viral load suppression to prevent liver cirrhosis and cancer
✔Off-label research into co-infections, though not recommended for HIV without combination ART.
⚠️Important Note: Telabee is NOT for HIV treatment. If you have HIV-HBV coinfection, consult your doctor for proper antiretroviral therapy.
Dosage & Administration
Recommended Dosage of Telabee 25Mg:
- 25 mg once daily with food
- No dose adjustment needed for mild/moderate kidney or liver impairment
Missed Dose?
Take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Do NOT double the dose.
| Patient Condition | Dosage |
| Adults (Normal Liver/Renal) | 1 tablet (25 mg) once daily with food |
| Renal Impairment | No adjustment (unless <15 ml/min) |
| Hepatic Impairment | Not recommended in Child-Pugh B or C |
⚠️Important: Take with food to improve absorption.
Contra-indication
✔ None (Source: Telabee IL-02)
Side Effects of Telabee 25 mg
Most side effects are mild.
Most Common Side Effects (≥5%):
- Headache
- Abdominal pain
- Nausea
- Fatigue
- Cough
- Back pain
Rare But Serious Side Effects:
- Lactic acidosis
- Liver toxicity
- Renal dysfunction
- Kidney issues
Drug Interactions of Telabee 25 Mg
Increased Risk with:
- NSAIDs (e.g., Ibuprofen)
- Aminoglycosides (e.g., Gentamicin)
- Antivirals (e.g., Cidofovir)
May reduce efficacy when combined with:
- Rifampin
- Carbamazepine
Safe combinations include:
- Sertraline
- Sofosbuvir
- Itraconazole
Warnings & Precautions
⚠ Severe HBV Flare-Ups: If stopped abruptly—always monitor after discontinuation.
⚠ HIV Testing: Required before initiating therapy.
⚠ HIV Resistance Risk: Do not use Telabee alone in HIV patients.
⚠ Kidney Function Tests: Needed before and during treatment.
⚠ Lactic Acidosis Risk: Rare but serious .
Use in Specific Populations
Pregnancy: No adverse fetal effects in animal studies; use only if necessary.
Lactation: Unknown if secreted in human milk; avoid breastfeeding.
Elderly Patients: Monitor kidney function closely.
Overdose Effects & Management
- Symptoms: Nausea, dizziness, kidney impairment
- Treatment: Supportive care + hemodialysis (if needed)
Storage Conditions
- Store below 25°C in a dry place and away from light.
- Keep away from children
Packing Information
- Each box: 10 tablets in Alu-Alu blister
Availability On Buying Telabee 25 mg Online
Where to Buy:
👉 EmergencyDrug.com – Global shipping
Ensure:
- Manufacturer authenticity (Jenphar/Radiant)
- Proper temperature packaging
Price & Generic Availability
Telabee 25 mg Price in Bangladesh: Approx. $40.00 per pack (Contact Local Pharmacy For More Info or Local Currency)
Generic Alternatives: Available under “Tenofovir Alafenamide” globally, however, here is a list of alternatives below:
| Brand Name | Dosage Form | Strength | Company |
| Alenvir | Tablet | 25 MG | Square Pharmaceuticals PLC |
| Alfavir | Tablet | 25 MG | Incepta Pharmaceuticals Ltd. |
| Nexataf | Tablet | 25 MG | Everest Pharmaceuticals Ltd. |
| Protovir | Tablet | 25 MG | Healthcare Pharmaceuticals Ltd. |
| T-Fovir A | Tablet | 25 MG | Drug International Ltd. |
| Tafecta / TAF | Tablet | 25 MG | Beacon Pharmaceuticals PLC |
| Tranbit | Tablet | 25 MG | Genvio Pharma Ltd. |
| Vironil-A | Tablet | 25 MG | UniMed UniHealth Pharmaceuticals Ltd. |
Conclusion
Telabee 25 mg tablet (Tenofovir Alafenamide) is a modern, safer, and effective treatment for chronic hepatitis B. With lower kidney and bone risks, it offers a better long-term safety profile than older tenofovir drugs. Patients finally have a medication they can rely on — for treatment that not only works but also protects.
Always follow your doctor’s advice, get regular check-ups, and never stop treatment abruptly. If you have any concerns, discuss them with your healthcare provider.
Stay informed, stay healthy! 💙
FAQs
Ques: Can Telabee 25 mg cure hepatitis B?
Ans: No, it suppresses HBV but does not cure it. Long-term treatment is often needed.
Ques: Is Telabee safe for kidney patients?
Ans: Yes, it has a better safety profile than older drugs like TDF, but should be avoided if creatinine clearance is under 15 ml/min and regular monitoring is still advised.
Ques: Can I take Telabee with alcohol?
Ans: Avoid excessive alcohol—it may worsen liver damage.
Ques: How long does Telabee tablet take to work?
Ans: Viral load reduction starts in weeks, but full suppression may take months.
Ques: What is Telabee 25mg used for?
Ans: Telabee is used to treat chronic hepatitis B infections in adults with stable liver function.
Ques: Where can I buy Telabee 25 mg online?
Ans: You can purchase it from licensed international pharmacies like EmergencyDrug.com.
Ques: Where can I buy Telabee 25mg in Bangladesh?
Ans: Available at pharmacies with a prescription. Avoid unauthorized online sellers.
Ques: What’s the difference between Tenofovir Alafenamide and Tenofovir Disoproxil?
Ans: TAF (Telabee) has lower side effects and requires a smaller dose than TDF.
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