Description
Product Features:
| Product Name | : Jakura |
| Generic Name | : Tofacitinib |
| Manufacturer | : Hetero Healthcare |
| Indication | : Rheumatoid Arthritis |
| Formulation | : Tablet |
| Strength | : 5 mg |
| Quantity | : 60 Tablets |
| Storage | : Room temperature |
| Registrations | : Export Only |
Indications and Uses of Jakura 5 mg
Therapeutic Indications
Jakura 5 mg is primarily prescribed for the following conditions:
Rheumatoid arthritis: A chronic inflammatory disorder that affects the joints.
Psoriatic Arthitis: Arthritis associated with psoriasis, a skin condition.
Ulcerative Colitis: A chronic inflammatory bowel disease that affects the lining of the colon.
Ankylosing Spondylitis: A kind of arthritis that mainly involves the spine.
In these conditions, Jakura 5 mg helps to reduce pain, swelling and stiffness in joints and improves physical function.
Pharmacology
Drug Classes
Jakura 5 mg is in a class of medications called Janus kinase (JAK) inhibitors. These two drugs act by inhibiting the activity of specific enzymes involved in inflammation.
Mechanism of Action:
Jakura 5 mg contains tofacitinib as an active substance that works by inhibiting janus kinase (JAK) enzymes, specifically JAK1 and JAK3 which are pertinent to the signaling pathways of multiple inflammatory cytokines. Jakura 5 mg works by blocking the enzymes that cause inflammation, reducing inflammation and relieving symptoms.
Dosage & Administration
Indication-based Dosage: For various conditions, Jakura 5 mg dosage would differ between individuals based on clinical judgement. You must follow your doctor instructions and keep prescribed dosage. Jakura 5 mg is usually taken orally in tablet form, two times a day.
Side Effects
Common side effects
- Headache
- Nausea
- Diarrhea
- Upper respiratory tract infections
Serious side effects
- Serious infections
- Blood clots
- Cancer
- Tears in the stomach or intestines
You should get in touch with your doctor right away if you have any serious or worrying side effects.
Use In Specific Populations
Pregnancy
It is a category C drug; it is harmful during pregnancy; it is taken only if the benefits are higher than the risks.
Lactation
It is not known whether Jakura 5 mg passes into breast milk. Discuss with doctor before breastfeeding while using this medication.
Precautions & Warnings
Gastrointestinal Events: Monitor perforations in at-risk populations.
Lab Monitoring: Recurrent blood lymphocytes, neutrophils, hemoglobin, and liver enzyme, lipids.
Vaccines: No live vaccines for the course of treatment.
Hematologic Abnormalities: Not Intended for use and should not be administered to individuals with severely low blood counts.
Renal & Liver Impairment: Adjust for moderate; avoid in severe hepatic impairment.
Cancer Risk: Higher risk of lymphoma and skin cancers.
Pregnancy & Breastfeeding: Only if vital; consult doctor.
Drug Interactions: Reduce dose with CYP3A4/CYP2C19 inhibitors; avoid CYP inducers.
Presentation
Storage Conditions
Store at room temperature (Below 30°) in a tightly closed container away from moisture and heat.
Manufactured by
The medicine is produced by Abyss Pharma Private Limited, Delhi, India.
Disclaimer: This information is provided solely for educational reasons and should not be considered medical advice. Always consult with your doctor or healthcare professional before taking any drug.
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