Tofacent 5 MG (Tofacitinib) – 60 Tablets

Description

Summary:

“You deserve to live with less pain—here’s how Tofacent 5  mg can help.”

Tofacent 5 mg (Tofacitinib) is indicated for treating adult patients with moderately to severely active rheumatoid arthritis who have not responded adequately or are intolerant to methotrexate. It can be used alone or in combination with methotrexate or other non-biologic disease-modifying antirheumatic drugs. It is a new treatments for rheumatoid arthritis patients as well as alopecia areata patients.

 

Introduction

Imagine waking up with stiff, swollen joints every morning. Simple tasks like opening a jar or climbing stairs become painful challenges. For millions with rheumatoid arthritis (RA), psoriatic arthritis (PsA), or ulcerative colitis (UC), this is a daily reality. And you say to yourself ,”I need medicine to relief from this severe pains.” This Janus kinase (JAK) inhibitor reduces inflammation by targeting immune system overactivity. It’s an affordable alternative to biologics like Xeljanz. 

 

Product Features of  Tab Tofacent 5 MG:

Brand Name:	Tofacent
Generic Name:	Tofacitinib
Strength:	5 mg (Five miligrams)
Form:	Oral Tablet
Class:	JAK Inhibitor / DMARD (Immunomodulator)
Dosage Form:	Oral tablet (Twice daily / BID)
Quantity:	60 Tablets
Storage:	Below 30°C
Registrations:	Export Only
Manufacturer:	Incepta Pharmaceuticals Ltd.
Exporter:	EmergencyDrug | Home of Generic Medicines (Online Pharmacy)

 

Tofacent 5 MG Price in USA/ Canada / UK/ Australia / South Africa / Ireland / Saudi Arabia/ Qatar/ UAE/ Kuwait/ Bahrain/ Egypt / Europe: $30.00

 

Composition

Tab Tofacent 5 mg: Each tablet contains Tofacitinib Citrate INN equivalent to Tofacitinib 5 mg

Tab Tofacent XR 11: Each Extended Release tablet contains Tofacitinib Citrate INN equivalent to Tofacitinib 11 mg.

 

What is Tofacent 5 MG?

Tofacent 5 MG is a brand name for the generic drug tofacitinib. It is available in tablet form and is typically taken orally, twice daily. Tab Tofacitinib is a Janus kinase (JAK) inhibitor, which means it blocks certain enzymes in the immune system that contribute to inflammation. By reducing inflammation, Tofacent 5 MG helps alleviate symptoms of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

It is a medication used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis, and ulcerative colitis.

More about tofacitinib mechanism of action.

 

What is Tofacent Used For? (Tofacent 5 mg Tablet Uses)

Tofacent tablet is primarily used in the management of several autoimmune diseases:

• Rheumatoid Arthritis: For adults with moderately to severely active rheumatoid arthritis, Tofacent 5 mg can help reduce joint pain, stiffness, and swelling, and slow the progression of joint damage. It may be used alone or in combination with other medications like methotrexate.
• Psoriatic Arthritis: In adults with active psoriatic arthritis, this medication can alleviate joint symptoms and improve skin manifestations of the condition.
• Ulcerative Colitis: Tofacent is used to treat adults with moderately to severely active ulcerative colitis, a chronic inflammatory bowel disease that affects the large intestine.
• Ankylosing Spondylitis: This medication is also approved for the treatment of adults with active ankylosing spondylitis, a type of arthritis that primarily affects the spine.
• Polyarticular Course Juvenile Idiopathic Arthritis (pcJIA): Tofacent tablet can be prescribed for children aged two and older with this form of juvenile arthritis.
• Limitations: Avoid using it with biologic DMARDs or strong immunosuppressants like Azathioprine and cyclosporine.

 

How Does Tofacent 5 mg Work?

Tofacent’s mechanism of action involves the inhibition of Janus kinases (JAKs). JAKs are enzymes that play a crucial role in the signaling pathways of cytokines, which are proteins that regulate inflammation and immune responses. By blocking these pathways, Tofacitinib reduces the production of inflammatory mediators, thereby decreasing the inflammation and symptoms associated with autoimmune disorders. Unlike biologics (injectables), it’s an oral tablet, making treatment easier.

Key Benefits of  Tab Tofacent 5 mg:

✔ Reduces joint pain & swelling
✔ Slows RA progression
✔ Improves mobility & quality of life

 

Dosage And Administration 

Administration of  Tofacent 5 Tablet

Before starting tab Tofacitinib 5 mg or Tofacitinib XR, ensure that the patient’s absolute lymphocyte count is at least 500 cells/mm3, absolute neutrophil count (ANC) is at least 1000 cells/mm3, and hemoglobin level is at least 9 g/dL.

 

Recommended Dosage of  Tofacent 5 Tablet

For Rheumatoid Arthritis recommended dosage is either Tofacitinib 5 mg twice daily or Tofacitinib XR 11 mg once daily. Patients with moderate to severe renal impairment or moderate hepatic impairment should take Tofacitinib 5 mg once daily.

 

For Psoriatic Arthritis with nonbiologic DMARDs, the dosage is the same as for Rheumatoid Arthritis. If the patient has moderate to severe kidney or liver issues, they should take Tofacitinib 5 mg tablet once daily.

 

For Ulcerative Colitis, start with Tofacitinib 10 mg twice daily or Tofacitinib XR 22 mg once daily for 8 weeks. Then, check how the patient is doing and switch to a maintenance dose depending on their response. If needed, they can keep taking the starting dose for up to 16 weeks. If the treatment isn’t working well enough, stop it.

 

💊 What If  I Forget to Take a Tofacent 5 mg Tablet?

Missing a dose can happen—but it’s important to handle it the right way:

👉 If you forget to take your Tofacent 5 mg tablet, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose. Do not take two tablets at once to make up for the missed one.

Doubling up can increase your risk of side effects like infections, headache, or elevated liver enzymes.

✅ Pro tip: Set a daily reminder or use a pill organizer to stay consistent. This medication works best when taken at the same time each day, typically morning and evening for the 5 mg formulation.

 

 🤢 What Are The Side Effects of Tofacent 5 mg?

Common Side Effects of  Tab Tofacent 5 mg

Rheumatoid and Psoriatic Arthritis:

• Upper respiratory tract infection
• Nasopharyngitis
• Diarrhea
• Headache

 

Ulcerative Colitis:

• Nasopharyngitis (cold-like symptoms)
• Elevated cholesterol levels
• Headache
• Upper respiratory tract infection
• Increased blood creatine phosphokinase
• Rash
• Diarrhea
• Herpes zoster

⚠  Most Serious Side Effects of Tofacent 5 mg (FDA Black Box Warning)

Severe Infections

Tofacitinib lowers the immune system’s defense, increasing the risk of serious infections.

Watch for:

• Fever, chills, night sweats
• Persistent cough (with or without blood)
• Shortness of breath
• Painful skin rash or blisters (shingles)
• Weight loss

Blood Clots (Deep Vein Thrombosis / Pulmonary Embolism)

Higher risk in adults over 50 with heart risk factors.

Watch for:

• Sudden chest pain or shortness of breath
• Rapid heartbeat
• Swelling, redness, or pain in legs

Heart Attack or Stroke

Watch for:

• Chest pain or pressure spreading to arm/jaw
• Sudden weakness/numbness on one side of the body
• Slurred speech or vision changes
• Dizziness or fainting

Cancer (Lymphoma, Lung Cancer, Skin Cancer)

Watch for:

• Unexplained lumps or swelling
• Chronic cough or coughing blood
• Unexplained weight loss
• New or changing skin spots/moles

Severe Allergic Reactions (Anaphylaxis)

Watch for:

• Swelling of lips, tongue, or throat
• Severe dizziness or fainting
• Difficulty breathing
• Hives or widespread rash

Gastrointestinal Perforation (Rare but Serious)

Watch for:

• Severe stomach pain
• Nausea/vomiting with fever
• Hard or bloated abdomen

Liver Damage

Watch for:

• Yellowing of skin or eyes (jaundice)
• Dark urine
• Right-sided abdominal pain
• Persistent nausea/loss of appetite

Low Blood Cell Counts

Watch for:

• Frequent or unusual infections
• Fatigue, weakness, pale skin
• Easy bruising or bleeding

✅ What to Do:
If you have any of these symptoms, stop taking Tofacent 5 mg and seek emergency medical help immediately.

Expert Insight:

“Patients on Tofacent should be monitored for infections. Live vaccines must be avoided.”
— Dr. Ahmed Khan, Rheumatologist

 

Precaution of  Tab Tofacent 5

If you are allergic to tofacitinib or have any other allergies, tell your doctor or pharmacist. The product may contain inactive ingredients, which can cause allergic reactions. Consult your pharmacist for more information.

 

Before using Tofacent 5 mg, inform your doctor or pharmacist about your medical history. Pay particular attention to conditions such as: blood clots (such as in the lungs and legs), blood/bone marrow disorders (such as anemia, low lymphocyte/neutrophil count), cancer, heart problems (such as a previous heart attack), kidney disease, liver disease (such as hepatitis B or C), lung disease, past/recent/current infections (such as tuberculosis, herpes zoster, HIV infection), current or past smoking, and other stomach/intestinal disorders (such as ulcers, diverticulitis), as well as stroke.

 

Tofacent 5 mg tablet can increase your risk of infection or worsen an existing infection. Avoid contact with people who have infections that can spread to others, such as chickenpox, measles, and the flu. For more information, consult your doctor.

 

Vaccine

Before receiving any immunizations or vaccinations, inform your health care provider that you are using tofacitinib. It would be best to avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
Diabetes, liver disease, phenylketonuria (PKU), or any other condition requiring dietary limitations or avoidance is advised. If you have questions about using this product safely, consult your physician.

 

If you plan on having surgery, tell your doctor about all the medications you are taking (including prescriptions, non-prescription, and herbal products). Using this medication may increase the risk of infection for older adults.

 

Tofacent 5 mg Uses in Pregnancy & Lactation

This medication should only be used when necessary during pregnancy. Consult your doctor about the risks and benefits. Let your doctor know if you intend to become pregnant or if you are already pregnant.

There are no adequate and well controlled studies in pregnant women. Physicians should use Tofacent oral tablet during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this medicine is excreted in human milk.

It is unknown whether this medication passes into breast milk. Do not use this drug while breastfeeding and for at least 18 hours after the last dose due to the potential risk to the infant. Before breastfeeding, consult your doctor.

 

Storage

Do not store above 30°C. Keep away from light and out of the reach of children.

 

Clinical Trials & Real‑World Data

ORAL Solo/Start/Scan: ~59–73% ACR20 by 3–6 months; significant inhibition of radiographic progression

Long-term extension ORAL Sequel: 9.5-year data, 3.4 IR for herpes zoster, 2.4 serious infections per 100 py, sustained efficacy

Post hoc 2023 analysis: Efficacy across prior treatment levels, better benefit/risk with fewer prior DMARDs.

 

Patient Experiences

✅ “After 3 months, my joint pain reduced by 70%.” — Maria, 52 (RA Patient)
⚠️   “Got shingles within 2 months—doctor paused treatment.” — John, 45

 

Summary Table

Aspect	Details
Drug Name	Tofacitinib (brand name: Tofacent)
Indications	RA, Psoriatic Arthritis, UC (and in some regions, ankylosing spondylitis, pcJIA)
Mechanism	JAK inhibitor—reduces inflammation
Common Dose	5 mg twice daily (immediate-release) or 11 mg once daily (XR)
Side Effects	Infections, headache, diarrhea, labs changes, CV risks
Serious Risks	TB, serious infections, blood clots, GI perforation, possible malignancy
Monitoring	CBC, LFTs, lipids, renal function, TB screening
Precautions	Avoid with live vaccines, in pregnancy/lactation without weighing benefits

 

How To Buy Tofacent 5 mg  Drug?

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Tofacent 5 mg Price in USA: ~$30 for 60 tablets of 5 mg (Export Brand)

Global: Delivering worldwide including United State (USA), United Kingdom (UK), Saudi Arabia, Dubai, Kuwait, Qatar, Philippines, Nepal, Malaysia, Indonesia, Thailand, Poland, Peru, South Korea, New Zealand, Netherlands, Georgia, France, Egypt, Australia, Germany, Canada, Uzbekistan, Lebanon, Mexico, Singapore, Vietnam, etc.

 

Where To Buy Tofacent 5 mg ?

Our ”https://emergencydrug.com/” Shop provides a lower cost of  Tofacent 5 mg drug. So buy Tofacent 5 mg capsules or tablets at our online shop at an affordable price compared to the other online pharmacy.

 

✅ Conclusion

Tofacent 5 mg (tofacitinib) is a well-established, FDA-approved JAK inhibitor providing rapid and long-lasting relief for RA—and helpful in PsA and UC. When used carefully (monitoring and dose adjustments), it offers a powerful tool in your therapeutic arsenal. Talk to your rheumatologist about suitability for your case.

 

FAQs

1. How long until Tofacent works?
Ans: Typically 2 weeks for symptom relief; 3 months for significant improvement (ACR20 ~60–69%).

2. Does Tofacitinib increase COVID-19 risk?
Ans: Yes, immunosuppressants may raise infection risks. Consult your doctor.

3. Can Tofacitinib cure rheumatoid arthritis?

Ans: No, but it slows progression and improves symptoms.

4. Best time to take Tofacent 5 mg tablets?

Ans: Morning & night for twice-daily dosing, or as prescribed.

5. Are there withdrawal symptoms if stopped?

Ans: Gradual tapering is recommended to prevent flare-ups.

 

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⚠️Disclaimer: This information is not exhaustive. For complete information, consult the full prescribing information and discuss any concerns with your doctor.

Note: The descriptions provided above are taken from the prescription information for Tofacent 5 mg (Tofacitinib), as provided by Incepta Pharmaceuticals Limited. Full prescription

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