Tofacent 5 MG (Tofacitinib) – 60 Tablets

Description

Tofacent 5 mg (Tofacitinib) is indicated for treating adult patients with moderately to severely active rheumatoid arthritis who have not responded adequately or are intolerant to methotrexate. It can be used alone or in combination with methotrexate or other non-biologic disease-modifying antirheumatic drugs.

Product Features:

Composition

Tofacent 5 mg: Each tablet contains Tofacitinib Citrate INN equivalent to Tofacitinib 5 mg

Tofacent XR 11: Each Extended Release tablet contains Tofacitinib Citrate INN equivalent to Tofacitinib 11 mg.

What is Tofacitinib?

Tofacitinib sold under the brand name Xeljanz, is a type of drug known as a Janus kinase (JAK) inhibitor. Tofacitinib is a medication used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis, and ulcerative colitis.

More about tofacitinib mechanism of action.

Tofacent 5 mg used for?

Rheumatoid Arthritis: It’s used in adults with moderately to severely active rheumatoid arthritis who didn’t respond well to methotrexate. It can be used alone or with methotrexate or other similar drugs.

Psoriatic Arthritis: It’s used in adults with active psoriatic arthritis who didn’t respond well to methotrexate or similar drugs.

Ulcerative Colitis: It’s used in adults with moderately to severely active ulcerative colitis.

Limitations: Avoid using it with biologic DMARDs or strong immunosuppressants like Azathioprine and cyclosporine.

Dosage And Administration

Administration

Before starting Tofacitinib 5 mg or Tofacitinib XR, ensure that the patient’s absolute lymphocyte count is at least 500 cells/mm3, absolute neutrophil count (ANC) is at least 1000 cells/mm3, and hemoglobin level is at least 9 g/dL.

Recommended Dosage

For Rheumatoid Arthritis recommended dosage is either Tofacitinib 5 mg twice daily or Tofacitinib XR 11 mg once daily. Patients with moderate to severe renal impairment or moderate hepatic impairment should take Tofacitinib 5 mg once daily.

For Psoriatic Arthritis with nonbiologic DMARDs, the dosage is the same as for Rheumatoid Arthritis. If the patient has moderate to severe kidney or liver issues, they should take Tofacitinib 5 mg tablet once daily.

For Ulcerative Colitis, start with Tofacitinib 10 mg twice daily or Tofacitinib XR 22 mg once daily for 8 weeks. Then, check how the patient is doing and switch to a maintenance dose depending on their response. If needed, they can keep taking the starting dose for up to 16 weeks. If the treatment isn’t working well enough, stop it.

Common Side Effects of  Tofacent 5 mg

Rheumatoid and Psoriatic Arthritis:

• Upper respiratory tract infection
• Nasopharyngitis
• Diarrhea
• Headache

Ulcerative Colitis

• Nasopharyngitis
• Elevated cholesterol levels
• Headache
• Upper respiratory tract infection
• Increased blood creatine phosphokinase
• Rash
• Diarrhea
• Herpes zoster

More about generic tofacitinib side effects.

Precaution

If you are allergic to tofacitinib or have any other allergies, tell your doctor or pharmacist. The product may contain inactive ingredients, which can cause allergic reactions. Consult your pharmacist for more information.

Tofacent 5 mg tablet can increase your risk of infection or worsen an existing infection. Avoid contact with people who have infections that can spread to others, such as chickenpox, measles, and the flu. For more information, consult your doctor.

Vaccine

Before receiving any immunizations or vaccinations, inform your health care provider that you are using tofacitinib. It would be best to avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
Diabetes, liver disease, phenylketonuria (PKU), or any other condition requiring dietary limitations or avoidance is advised. If you have questions about using this product safely, consult your physician.

If you plan on having surgery, tell your doctor about all the medications you are taking (including prescriptions, non-prescription, and herbal products). Using this medication may increase the risk of infection for older adults.

Use in Pregnancy & Lactation

This medication should only be used when necessary during pregnancy. Consult your doctor about the risks and benefits. Let your doctor know if you intend to become pregnant or if you are already pregnant.

There are no adequate and well controlled studies in pregnant women. Physicians should use Tofacent oral tablet during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this medicine is excreted in human milk.

It is unknown whether this medication passes into breast milk. Do not use this drug while breastfeeding and for at least 18 hours after the last dose due to the potential risk to the infant. Before breastfeeding, consult your doctor.

Storage

Do not store above 30°C. Keep away from light and out of the reach of children.

Countries where our service provided

Delivering worldwide including United State (USA), United Kingdom (UK), Saudi Arabia, Dubai, Kuwait, Qatar, Philippines, Nepal, Malaysia, Indonesia, Thailand, Poland, Peru, South Korea, New Zealand, Netherlands, Georgia, France, Egypt, Australia, Germany, Canada, Uzbekistan, Lebanon, Mexico, Singapore, Vietnam, etc.

Our ”EmergencyDrug” Shop provides a lower Cost of  Tofacent 5 mg. So buy Tofacent 5 mg capsules or tablets at our online shop at a competitive price.

Note: The descriptions provided above are taken from the prescription information for Tofacent 5 mg (Tofacitinib), as provided by Incepta Pharmaceuticals Limited. Full prescription

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