Tofacinix 11 MG (Tofacitinib) – 30 Tablets

Description

Tofacinix 11mg tablet is a specific dosage strength of the medication Tofacitinib. Tofacitinib is an oral Janus kinase (JAK) inhibitor used to treat various autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis, among others

Product Features:

Tofacinix Dosage

The dosage of Tofacitinib 11 mg can vary depending on the specific autoimmune condition being treated and the individual patient’s medical history. It is of utmost importance to adhere to the dosage and instructions provided by your healthcare provider. Typically, Tofacitinib tablet taken once daily.

Rheumatoid Arthritis

Doctors may prescribe a higher dose, such as 11 mg once daily, to some patients depending on the severity of their condition and their response to treatment.

Psoriatic Arthritis

As with rheumatoid arthritis, some individuals may be prescribed tofacitinib 11 mg once daily.

Ulcerative Colitis

The recommended starting dose for adults is often tofacitinib 10 mg taken orally twice daily for induction for 8 weeks and 11 mg given once daily for maintenance.

Warnings And Precautions

Patients undergoing treatment with Tofacitinib have reported serious and sometimes life-threatening infections caused by various pathogens, including bacteria, mycobacteria, invasive fungi, viruses, and other opportunistic microorganisms. Among the most frequently observed serious infections associated with Tofacitinib use are pneumonia, cellulitis, herpes zoster (shingles), urinary tract infections, diverticulitis, and appendicitis.

In addition to these common infections, Tofacitinib has also linked patients to opportunistic infections such as tuberculosis and other mycobacterial infections, cryptococcosis, histoplasmosis, esophageal candidiasis, pneumocystosis, multidermatomal herpes zoster, cytomegalovirus infections, BK virus infection, and listeriosis.

It’s worth noting that some patients have developed disseminated infections rather than localized ones. This has occurred more frequently in individuals who were also taking other immunomodulating drugs like methotrexate or corticosteroids alongside Tofacitinib.

Healthcare providers should exercise caution when considering the use of Tofacitinib in patients with ulcerative colitis (UC). It is advisable to avoid Tofacinix in individuals with active and serious infections, including those that are localized. Before initiating Tofacitinib treatment, healthcare providers should carefully evaluate the potential risks and benefits, especially in patients who have:

• Chronic or recurrent infections.
• Been exposed to tuberculosis.
• Suffered from serious or opportunistic infections.
• Resided in or traveled to areas where tuberculosis or endemic fungal infections are prevalent.
• Underlying medical conditions that may make them more susceptible to infections.

Always follow your doctor’s instructions and attend regular check-ups while closely monitor for the development of signs and symptoms of infection during and after treatment with this tablet.

Side Effects

Most common side effects are:

• Upper respiratory tract infections
• Headache
• High blood pressure (hypertension)
• Increased levels of liver enzymes
• Nausea
• Diarrhea
• Changes in blood cell counts
• Elevated levels of cholesterol and triglycerides
• Skin rash
• Elevated creatinine levels (a marker of kidney function)

Pregnancy and Lactation

Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Tofacinix uses during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this medicine is excreted in human milk. Caution exercised when this product administered to a nursing woman.

Tofacitinib Drug Interactions

With medicine: Tofacitinib exposure increase when Tofacitinib is co-administered with potent inhibitors of cytochrome P450 (CYP) 3A4 (e.g., ketoconazole) and CYP2C19 (e.g., fluconazole). Use of Tofacitinib in combination with biologic DMARDs or potent immune suppressants such as azathioprine and cyclosporine not recommend.

With food and others: Avoid taking Tofacitinib with grapefruit juice and to avoid grapefruit juice completely during Tofacitinib treatment.

Overdose

There is no specific antidote for overdose with Tofacitinib 11 mg. In case of an overdose, it recommends that the patient monitor for signs and symptoms of adverse reactions.

Storage Condition

Store below 25°C. Do not remove desiccant. Dispense in the original container. Keep it out of the reach and sight of children.

How Supplied

This tablet: Each HDPE contain 30 tablets, a silica gel desiccant, and a polyester coil with a child-resistant closure

The country where our services are provided

Delivering worldwide including United State (USA), United Kingdom (UK), Saudi Arabia, Dubai, Kuwait, Qatar, Philippines, Nepal, Malaysia, Indonesia, Thailand, Poland, Peru, South Korea, New Zealand, Netherlands, Georgia, France, Egypt, Australia, Germany, Canada, Uzbekistan, Lebanon, Mexico, Singapore, Vietnam, etc.

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