Description

Elbonix (Eltrombopag ) is an orally bioavailable, small-molecule TPO-receptor agonist that interacts with the transmembrane domain of the human TPO-receptor and initiates signaling cascades that induce proliferation and differentiation from bone marrow progenitor cells. Elbonix is available in tablet form for oral administration.

Indications

• Improves chronic ITP & SAA effectively
• Effective in chronic hepatitis C related thrombocytopenia
• Increases & maintains platelet counts

Product Features

Working Principle Eltrombopag

Eltrombopag is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. Platelets help to reduce or prevent bleeding.

Uses Elbonix

Eltrombopag is used for low platelet count due to ITP or HCV infection. That treat low platelet count due to chronic immune (idiopathic), thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infection. Eltrombopag is also use to treat severe aplastic anemia.

Side Effects

Nausea, Diarrhea, Upper respiratory tract infection, Vomiting, Increased liver enzymes, Muscle pain, Urinary tract infection.

Thrombocytopenia

A condition in which there is a lower-than-normal number of platelets in the blood. It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues.

Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries.

A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000 per microliter.

Signs and Symptoms

Thrombocytopenia signs and symptoms may include:

•  Easy or excessive bruising (purpura)
•  Superficial bleeding into the skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on the lower legs
•  Prolonged bleeding from cuts
•  Bleeding from your gums or nose
•  Blood in urine or stools
•  Unusually heavy menstrual flows
•  Fatigue
•  Enlarged spleen
•  Jaundice

Causes 

Thrombocytopenia caused due to:

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