Venex 100 MG (venetoclax) – 120 Tablets

Description

Product Features:

Venex 100: Each tablet contains Venetoclax INN 100 mg.

Venex 100 mg (venetoclax) is a BCL-2 inhibitor indicate for the treatment of patients with chronic lymphocytic leukemia (CLL) with 17p deletion, as detected by an FDA approved test, who have received at least one prior therapy.

Indications:

Venex 100 mg (Venetoclax) is a small molecule type of targeted therapy. It is a pill that promotes apoptosis, a common way by which cells die. It does this by binding to BCL-2, an anti-apoptotic protein. Overexpression of BCL-2 has been demonstrated in CLL cells where it mediates tumor cell survival and has been associated with resistance to chemotherapies. It helps restore the process of apoptosis by binding directly to the BCL-2 protein, displacing pro-apoptotic proteins. It blocks an important pathway that promotes cell survival in tumor cells that overexpress BCL-2, so capsule causes cells to die (pro-apoptotic).

Dosage & Administration

• It is a tablet, taken by mouth.
• It take orally once daily with a meal and water.
• Dosage adjusted base on side effects.
• Take exactly as prescribe.
• Swallow tablets whole. Do not crush, chew, break or dissolve tablets.
• Do not change your dose or stop.

The amount of that medicine you will receive depends on many factors, your general health or other health problems, and the type of cancer or condition become treated.

Side Effects

Important things to remember about the side effects of venetoclax:

Most people do not experience all of the side effects listed.
Side effects are often predictable in terms of their onset and duration.
Side effects usually reversible and often improve or go away after treatment stop.
There are many options to help minimize or prevent side effects.
There is no relationship between the presence or severity of side effects and the effectiveness of the medication.

Adverse Reactions

In CLL/SLL patients dosed with Venex 100 mg in a steady state (after ramp-up phase), consider alternative agents or modify the dose of Venex 100 mg and increase the frequency of monitoring for adverse actions.

In AML patients, dose-adjust and monitor for AEs more often.

Manufacturer by

Venex 100 mg is specifically manufactured and marketed by Drug International Limited (established in 1974), one of the leading pharmaceuticals companies of Bangladesh.

Venex 100 mg is drug which was licensed to Drug International Limited.

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Disclaimer: This information is provided solely for educational reasons and should not be considered medical advice. Always consult with your doctor or healthcare professional before taking any drug.