Description

Product Name: Xeljanz

Generic Name: Tofacitinib

Formulation: Tablets

Available Pack Size: 60’s in a bottle

Available Strengths: 5 mg

Manufacturer: Pfizer Inc.

Xeljanz is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis-pcJIA). It helps to decrease pain/tenderness/swelling in the joints. Xeljanz is also used to treat a specific bowel disease (ulcerative colitis). It helps reduce ulcerative colitis symptoms, such as diarrhea, rectal bleeding, and stomach pain.

What Xeljanz is and what it is used for

Xeljanz is a medicine that contains the active substance tofacitinib. Xeljanz is used for the treatment of the following inflammatory diseases:

• rheumatoid arthritis
• psoriatic arthritis
• ulcerative colitis
• ankylosing spondylitis
• polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis

Rheumatoid arthritis
Xeljanz is used to treat adult patients with moderate to severe active rheumatoid arthritis, a long-term disease that mainly causes pain and swelling of your joints.
Xeljanz is used together with methotrexate when previous rheumatoid arthritis treatment was not sufficient or was not well tolerated. Xeljanz can also be taken on its own in those cases where methotrexate treatment is not tolerated or treatment with methotrexate is not advised. Xeljanz has been shown to reduce pain and swelling of the joints and improve the ability to perform daily activities, when given on its own or together with methotrexate.

Psoriatic arthritis
Xeljanz is used to treat adult patients with a condition called psoriatic arthritis. This condition is an inflammatory disease of the joints, often accompanied by psoriasis. If you have active psoriatic arthritis you will be first given another medicine to treat your psoriatic arthritis. If you do not respond well enough or the medicine is not tolerated, you may be given Xeljanz to reduce the sign and symptoms of active psoriatic arthritis and improve the ability to perform daily activities. Xeljanz is used together with methotrexate to treat adult patients with active psoriatic arthritis.

Ankylosing spondylitis
Xeljanz is used to treat a condition called ankylosing spondylitis. This condition is an inflammatory disease of the spine.
If you have ankylosing spondylitis, you may first be given other medicines. If you do not respond well enough to these medicines, you will be given Xeljanz .
Xeljanz can help to reduce back pain, and improve physical function. These effects can ease your normal daily activities and so improve your quality of life.

Ulcerative colitis
Ulcerative colitis is an inflammatory disease of the large bowel. Xeljanz is used in adult patients to reduce the signs and symptoms of ulcerative colitis when you did not respond well enough or were intolerant to previous ulcerative colitis treatment.

Polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis
Xeljanz is used for the treatment of active polyarticular juvenile idiopathic arthritis a long-term disease that mainly causes pain and swelling of your joints, in patients 2 years of age and older. Xeljanz is also used for the treatment of juvenile psoriatic arthritis, a condition that is an inflammatory disease of the joints often accompanied by psoriasis, in patients 2 years of age and older.
Xeljanz can be used together with methotrexate when previous treatment for polyarticular juvenile idiopathic arthritis or juvenile psoriatic arthritis was not sufficient or was not well tolerated. Xeljanz can also be taken on its own in those cases where methotrexate treatment is not tolerated or treatment with methotrexate is not advised.

Warnings and precautions

Talk to your doctor or pharmacist before taking Xeljanz:

• if you think you have an infection or have symptoms of an infection such as fever, sweating, chills, muscle aches, cough, shortness of breath, new phlegm or change in phlegm, weight loss, warm or red or painful skin or sores on your body, difficulty or pain when swallowing, diarrhoea or stomach pain, burning when you urinate or urinating more often than normal, feeling very tired
• if you have any condition that increases your chance of infection (e.g., diabetes, HIV/AIDS, or a weak immune system). Tell your doctor immediately if you feel unwell. Xeljanz can reduce your body’s ability to respond to infections
• if you have or have a history of tuberculosis or have been in close contact with someone with tuberculosis. Your doctor will test you for tuberculosis before starting Xeljanz and may retest during treatment
• if you have any chronic lung disease
• if you have liver problems
• if you have or had hepatitis B or hepatitis C, the virus may become active while you are taking Xeljanz. Your doctor may do blood tests for hepatitis before you start treatment with Xeljanz
• if you are older than 65 years, if you have ever had white blood cell cancer, lung cancer and other cancers (such as breast, melanoma, prostate and pancreatic), and also if you are a current or past smoker, Xeljanz may increase your risk of certain cancers
• if you are at high risk of developing skin cancer, your doctor may recommend that you have regular skin examinations while taking Xeljanz
• if you have kidney problems
• if you are planning to get vaccinated, tell your doctor. Certain types of vaccines should not be given when taking Xeljanz
• if you have heart problems, high blood pressure, high cholesterol, and also if you are a current or past smoker.

See other Tofacitinib generic medicine:

Tofacinix (Tofacitinib) 5 MG 

Tofacinix (Tofacitinib) 11 MG 

Tofacent (Tofacitinib) 5 MG