The current emergency drug price guidelines indicate that the cost of a 5 mg tablet of tofacitinib, known as Tofacinix, is $65, while the 11 mg tablet is priced at $95. These prices do not include delivery charges, which can vary significantly based on the country or region of purchase.

 

What is Tofacitinib?

Tofacitinib is a medication classified as a Janus kinase (JAK) inhibitor. It is used to treat autoimmune and inflammatory conditions by targeting specific enzymes involved in the immune system’s signaling pathways. By inhibiting Janus kinases, tofacitinib helps modulate the immune response and reduce inflammation associated with certain diseases.

 

Brand Name Prescription Products

NAME	DOSAGE	STRENGTH	ROUTE	MANUFACTURER	QUANTITY
Xeljanz	Lenvaxen 10 mg Tablet	5 mg	Oral	Pfizer Inc	60 Tablets
Tofacent	Tablet	5 mg	Oral	Incepta Pharmaceuticals Ltd	60 Tablets
Tofacinix	Tablet	5 mg	Oral	Beacon Pharmaceuticals Ltd	30 Tablets
Tofacinix	Tablet, extended release	11 mg	Oral	Beacon Pharmaceuticals Ltd	30 Tablets

Use of Tofacitinib

Tofacitinib is used in the treatment of several autoimmune conditions, including:

• Rheumatoid arthritis: To reduce signs and symptoms and inhibit structural damage.
• Psoriatic arthritis: To alleviate joint symptoms and improve physical function.
• Ulcerative colitis: To induce and maintain remission in adults with this inflammatory bowel disease

Mechanism of Action

Tofacitinib works by inhibiting the activity of Janus kinases (JAKs), which are enzymes involved in the signaling pathways of various cytokines and growth factors. By blocking these pathways, tofacitinib helps regulate the immune response and reduce inflammation.

 

People Also Ask (FAQ)

Question: Does xeljanz cause weight gain?

Answer: Xeljanz and Xeljanz XR do not cause either weight gain or weight loss.

 

Question: How many carbon atoms are present in tofacitinib?

Answer: The chemical compound tofacitinib pyrrolopyrimidine is represented by the molecular formula C16H20N6O. This indicates the presence of 16 carbon atoms, 20 hydrogen atoms, 6 nitrogen atoms, and one oxygen atom in its structure.

 

Question: How long does it take for xeljanz to work?

Answer: Although enhancements in physical function and a decrease in the count of painful, tender, and swollen joints may commence within as little as two weeks, it might take some patients up to three to four months to observe an amelioration in their symptoms.

 

Question: Can you take xeljanz while pregnant?

Answer: No, The use of this medication during pregnancy can pose risks to your unborn baby.

 

Question: How long does xeljanz stay in your system?

Answer: Upon oral administration of Xeljanz, peak plasma concentrations are achieved within 0.5 to 1 hour. The elimination half-life is approximately 3 hours, and there is a proportional increase in systemic exposure within the therapeutic dose range. Steady-state concentrations are established within 24 to 48 hours.